7.Other work related to chemistry researchand development.

岗位职责：

1. 根据公司战略需求，进行药学板块（原料药，制剂，质量）的规划和目标制定；

2. 负责制定化学新药项目CMC研究方案并领导团队进行实施；

3. 作为CMC技术专家，解决CMC研发中的技术困难，负责申报资料中药学板块；

4. 负责药学研发团队日常管理，建立高绩效的团队目标并组织实施；

5.领导团队与其他团队及部门进行高效沟通合作。

任职资格：

1. 博士以上学历，有机化学，合成化学，化工相关专业，至少5年以上医药企业或CRO, CDMO化药中间体，原料药工艺研发，生产，管理工作经验；

2. 熟悉化学药研究、GMP相关法规，有多个成功申报创新药或仿制药项目经历;

3. 有较强的领导、沟通、协调及计划组织能力;

4. 有良好的英语能力，可用英文进行书面工作交流。

岗位职责：

1. 设计高质量的化合物库；

2. 开发可靠的化学反应和合成方法；

3. 为库化学团队提供专业的技术支持，解决问题；

4. 建立高绩效团队，保障团队安全，健康，环境。

任职要求：

1. 有机化学，药物化学或相关专业博士以上学历；

2. 3-5年以上药物工业工作经验；

3. 结果导向，良好的自我激励意识，精力充沛；

4. 流利的中英文听说读写能力；

5. 具备分子库设计和合成工作经验者优先；

6. 具有早期药物研发经验者优先。

岗位职责：

1.负责1-2个项目的研发，负责设计目标化合物和库化合物的合成路线； 

2.根据需要对合成路线进行调整，保证各个项目按时顺利完成； 

3.审核研究员的合成路线、实验数据，确保其正确性和完整性； 

4.对项目进行归纳总结、撰写项目报告和科学论文； 

5.协助上级保证实验室的安全运作。

任职资格：

1.具有有机化学、药物化学等化学相关专业博士学位；

2.专业知识优秀，对小分子新药研发有一定基础；

3.热爱新药研发工作；

4.良好的英语能力；

5.优秀的团队合作能力；

6.有多步合成研发工作经验者优先。

岗位职责：

1.独立完成与公司项目相关的有机合成任务；

2.在指导下完成药物化学相关实验设计；

3.撰写项目报告相关部分；

4.实验室仪器日常维护管理；

5.承担部分员工培训工作；

6.确保自身和与工作相关的安全，环境和健康

任职要求：

1.有机化学，药物化学等化学相关专业本科及以上学历；        

2.优秀的实验设计和动手能力；

3.热爱从事新药研发工作；

4.优秀的学习能力和团队合作精神；

5.有多步合成研发工作经验者优先。

如您对该职位感兴趣，欢迎将详细简历及研究总结发送至邮箱：human.resources@hitgen.com

我们的联系方式：028-85197385(8406)

Job Description：

1. Lead a multi-disciplinary unit (structural biology, medicinal chemistry, in vitro and in vivo biology, process and formulation, etc) of approximately 90 people to progress innovative discovery projects from target nomination to clinical trials and collaboration licensing;

2. Ensure the unit meet the annual business, research and organizational development objectives set by the company;

3. Develop research and project portfolio strategy;

4. Implement the strategy through effective project management and decision making;

5. Build the organization and people for sustainable project delivery and growth;

6. Ensure the unit operations meeting the safety and relevant regulations;

7. Work with the business develop team to provide scientific and project support for external collaborations and licensing;

8. Provide specific scientific and technical input to projects where needed;

9. Establish a network of scientific collaboration partners;

10. Contribute to company's overall strategy and management.

Requirements:

1. PhD in Biology, Medicine or closely related fields;

2. Expertise and track record in discovery biology, pharmacology, or translational science will be essential;

3. Extensive experience in contributing and leading drug discovery projects from target nomination to clinical development will be required;

4. More than 15 years of relevant experiences in small molecule drug discovery, especially the experience gained in the research centers of major pharmaceutical , biotechnology companies or leading academic centers will be an advantage;

5. Experience in leading large teams will be required;

6. Excellent skills in organization, decision-making, and communication;

7. Capability to analyze and resolve problems in a timely manner;

8. Excellent verbal and written communication skills (English);

9. Ability to work effectively in cross-functional interactions;

10. Strong commercial awareness will be desirable.

Job Description:

Requirements:

Job responsibilities

1、Develop and validate biochemical/biophysical tools to characterize recombinant proteins.

2、 Biochemical and biophysical characterization of small molecules in functional and binding assays, selection of DNA encoded library against different drug targets.

3、Actively participate in the project team and collaborate extensively to deliver hit in a timely manner.

4、Review and provide expert scientific input into project regarding DNA encoded library selection design.

5、 Prepare SOPs, write assay and test report, present project summary.

6、 Ensure work is conducted in accordance with project design.

7、 Lead the team and provide innovative insight into the team.

Qualifications

1、Doctorate degree with working experience in biochemistry, biophysics, molecular biology, cell biology, pharmaceutical science or other related fields.

2、 Strong background in cellular and molecular biology is required, extensive hands-on experience in biochemical and biophysical assay (ELISA, HTRF, FP, SPR, TSA, etc.), molecular cloning, PCR/qPCR, SDS-PAGE, cell culture, transfection and cell assay is preferred.

3、Previous experience in high throughput screening, small molecule screening, covalent inhibitor screening, phage display, SELEX or other assay approaches relevant to drug discovery is preferred.

4、Excellent trouble-shooting, multitasking and interpersonal skills.

5、Able to provide technical and scientific guidance to other colleagues.

6、Able to rapidly learn new techniques, capable of independent and innovative scientific thinking,

7、 Excellent oral and written skills in English.

岗位职责：

1.承担并完成assay方法建立，DNA编码化合物库筛选任务及后期化合物评价；

2.与项目团队一起进行整个筛选任务的推进（包括后续数据分析、筛选方案调整等）；

3.领导团队进行技术创新；

4.参与制定项目研发计划，确保项目顺利进行；

5.项目进展汇报总结；

6.进行科学文档撰写；

7.指导生物实验室的工作；

8.协调研发工作开展。

任职要求：

1.分子生物学，酶学或药学等生物技术相关专业硕士及以上学历，具有发表高质量学术论文经历的候选人优先考虑，硕士需2年以上医药研发工作经验；

2.熟悉分子生物学，酶学基本理论，熟悉蛋白标签，蛋白质及小分子相互作用，小分子作用评价（酶学，结合实验测定），熟悉荧光定量PCR，蛋白及核酸凝胶电泳，细胞培养转染表达，分子克隆等实验操作；

3.有小分子药物靶点包括激酶、蛋白酶、蛋白相互作用等药物筛选经验（高通量筛选，噬菌体展示，SELEX等）或相关工作经历者优先；

4.思维缜密，自主学习，善于查阅文献、灵活思考问题，能发现并及时解决研发过程中遇到的技术问题，能独立设计实验方案并执行操作，推动项目运行；

5.开发新技术方法，优化平台建设。指导他人，具有一定的领导力；

6.具有英文文献阅读和英文实验报告撰写能力，英文听说读写熟练。

Job Description:
1. Lead a team of pharmacokinetics scientists to provide high quality data, interpretation, insight and reports to the drug discovery projects in a timely manner to enable effective project decision making; Provide effectively guidance in study design, protocol development and studyg execution of GLP and non-GLP pharmacokinetic, toxicokinetics, and ADME (as needed) studies; Provide input to the study designs in in vivo non-GLP and GLP pharmacology and toxicology studies;Supervise, assist and mentor contributing scientists on pharmacokinetic analysis, data interpretation and report writing; 
2. Ensure the capability meet the annual business, research and organizational development objectives set by the discovery project unit;
3. Provide specific scientific and technical input to projects where needed, eg, act as study director or principal investigator responsible for externally conducted PK, TK and ADME (as needed) studies as appropriate;Interact closely with other managers and contributing scientists tasked with bioanalytical assay development, and/or sample analysis to ensure seamless and timely transfer of bioanalytical and ADA data to the Preclinical PK/PD team;  
4. Ensure the capability operations meeting the safety and relevant regulations (eg, SOPs and GLP standards), eg, interact with the Scientific Writing Team in the creation of preclinical PK/TK written and tabulated summaries for IND and BLA applications, as well as IBs, annual updates and other regulatory activities;
5. Provide leadership in the interactions with external collaborations （eg, CROs）;
6. Develop the capability strategy to ensure scientific excellence, quality of output and operational efficiency;
7. Drive continuous improvements to obtain operational efficiency and reliability in delivering results to projects; 
8. Drive innovation in pharmacokinetics capability to meet discovery project unit’s medium and long term development goals; 
9. Build the organization and people for sustainable project delivery and growth;

10. Contribute to Discovery Projects Unt’s overall strategy and management.

Requirements:                       

1. PhD in pharmacokinetics or pharmacodynamics or closely related filed;
2. Expertise and track record in PK and bioanalysis in drug discovery research will be essential;
3. Extensive experience in contributing and leading small molecule drug discovery projects will be required;
4. Approximately 5 or more years of relevant experiences in PK and bioanalysis experimental design, data collection and interpretation, especially the experience  gained in the research centers of major pharmaceutical , biotechnology companies or leading academic centers will be an advantage;
5. Excellent organizational, decision-making, inter-personal relations, and communication skills;
6. Ability to analyze and resolve problems in a timely manner;
7. Excellent verbal and written communication skills (Chinese and English);
8. Ability to work in a team environment with cross-functional interactions.

岗位职责：

11. 提供临床需求及科学指导确保新药立项的临床相关性及临床开发的可行性。

任职要求：

6.良好的中英文阅读写作能力。

工作地点：北京

4.结果导向，责任心强，良好的协调沟通能力。

工作地点：北京

岗位描述：

1. 确定和建立潜在客户，通过深入了解客户组织与需求，建立和维护良好、长期、稳定的客户关系，取得客户信任，规划和统筹所有客户的销售活动；

2. 制定有针对性的营销策略，开展富有市场竞争力的市场活动，熟悉了解公司所能提供的所有服务和产品，抓住交叉销售的机会；

3. 跟进商业合同文件的处理，推动商业合作的完成，运用CRM系统维护客户信息及资源；

4. 定期进行销售工作总结汇报。

任职要求：

1. 本科以上学历，化学、医药等相关专业；

2. 3年以上生物医药行业商务开发工作经验，有可被证明的销售业绩记录；

3. 高度的自我管理能力和自我激励意识；

4. 工作地点北京，上海或成都。

工作职责：

1、负责董事长日常行程规划、安排及重要日程提醒，处理和董事长有关的各种接待工作；

2、协助董事长进行工作安排及协调，及时传达各项指令，与高管团队积极配合，督促、督办、跟进各项工作的落实与反馈；

3、负责公司各项重要会议筹备和安排，制定会议流程，准备会议议题，下发会议通知，撰写会议纪要；

4、及时向董事长呈报各部门递交审核的各类文件，并做好分类、预处理、反馈工作；

5、负责董事长有关文件的起草、修改、预审核，整理呈报董事长的各类文书、文件、报告、总结及其他材料，并对相关文件进行档案管理；

6、协助董事长处理对外公共关系（政府、客户等），相关事务的协调与沟通，关系维护与信息对接，协助处理相关的商务接待工作；

7、完成董事长交待的其他临时安排或突发性的工作，包括但不限于翻译、稿件信函撰写。

任职资格：

1、本科以上学历，5年以上董事长秘书/助理工作经验，具备生物医药企业工作经验者优先；

2、在纯英语环境下工作过，英语听说读写流利，英语八级优先；

3、精通现代办公应用，有较强的文字功底，能够独立撰写稿件；

4、形象气质佳，谈吐大方、举止得体，具有很好的亲和力和协调能力，熟悉商务接待礼仪；

5、做事认真严谨、反应敏捷，具有较强的团队协作精神、沟通技巧、组织规划能力，能够承受工作压力，高度的工作责任心。

Job Description：

1. Lead HitGen's computational sciences capability, consisting of specialist teams for DNA encoded library (DEL) design, DEL synthesis data mining, screening data analysis/mining, cheminformatics, bioinformatics, computer-aided drug design, virtual screening, artificial intelligence applications in drug discovery projects;
2.Ensure the capability meets the annual business, research and organisational development objectives set by the company;
3.Develop the capability strategy to ensure scientific excellence, quality of output, and operational efficiency;
4.Drive continuous improvements to obtain operational efficiency and reliability in delivering results to projects;
5.Drive innovation in assay and screening to meet the Lead Generation Unit’s medium and long term development goals;
6.Build the organisation and people for sustainable project delivery and growth;
7.Ensure the capability's operations meet the safety and relevant regulations;
8.Provide leadership in interactions with external collaborators;
9.Provide specific scientific and technical input to projects where needed;
10.Contribute to the company's overall strategy and management. 

Requirements:
1.PhD in computational chemistry, bioinformatics, computational sciences, or related fields;
2.10+ years of experience and track record in the development and/or applications of computational chemistry, molecular modelling, drug design and data analysis methods and software for drug discovery in the pharmaceutical industry or an equivalent setting;
3.Demonstrated experience in leading computational sciences team focused on structure-based drug design, virtual screening, QSAR, pharmacophore development, cheminformatics, bioinformatics, and/or machine learning;
4.Proficiency in a programming languages (such as C/C++, Python, Java, etc), computational software (such as Schrodinger) and a good working knowledge of common databases, resources and tools;
5.Proficiency in working with commonly used operating systems such as Unix/Linux, Windows for workstations and computing farms;
6. Strong ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact;
7. Strong English (Chinese also desirable) verbal and written communication skills to convey complex concepts and computational analyses to influence diverse audiences. 

岗位职责：

1. 优化现有生物信息学分析流程和系统，同时辅助搭建新的自动化生物信息学分析管线；

2. 分析基因组，转录组，表观遗传学数据以及公共数据库相关数据预测和发现潜在的药物靶点；

3. 对临床试验中生物标志物的分析及预测，对临床试验中药物反应的数据进行分析和解读,具有新项目的独立研究和分析的能力；

4. 协助客户提出实验方案，为客户提供技术指导。

任职要求：

1. 生物信息学及相关专业博士学位；

2.具有3年以上项目或工作经验；

3. 熟练掌握Java/Python/Perl/R中至少一种编程语言,具有基因组学、转录组学，项目开展经验,有表观遗传学分析经验者优先。