Welcome to HitGen

Capabilities

One-stop Technology Platform to Accelerate Drug Discovery and Development

Capabilities
  1. Capabilities
  2. Structure analysis

Structure analysis

Over the last few years, we have solved over dozens of target protein-small molecule cocrystal structures. For each protein crystallography project, we accelerate data processing and structure solutions via automated programs, meanwhile, the essential steps, like ligand fitting and finalization of the structures, are performed manually by our experienced crystallographers.


Crystal structures will be solved with molecular replacement or advanced de novo phasing techniques, followed by a detailed comparative analysis of the protein co-crystal structures, with the important interactions and the ligand-induced conformational changes highlighted.


Our experts verify and interpret every single structure carefully before delivery. All structures delivered passed our quality control criteria, that is, the PDB standard.

 

 

X-Ray Diffraction and Structure Determination


                                              image.png

 


Thanks for reading!

For more details on how we can advance your innovative drug discovery projects
验证码
By submitting your information, you acknowledge having received, read and understood our Privacy Notice as made available above.

We use cookies to provide a better web experience.
By using our site, you acknowledge our use of cookies and please read our Cookie Notice for More information