Synthetic Chemistry

HitGen Chemical Services: Innovation - Driven and Precision - Empowered

In the cutting - edge field of global drug R&D, CD Hitech (Chengdu headquarters) has established a comprehensive chemical service system with its outstanding professional capabilities and advanced technological facilities, providing efficient and reliable solutions for clients.

Professional Team, Leading with Wisdom

CD Hitech has assembled an elite team consisting of over two hundred professional chemical synthesis personnel. They are proficient in various complex chemical reactions and, with their profound professional knowledge and rich practical experience, continuously explore and innovate in the field of medicinal chemistry. Team members collaborate closely, committed to transforming every chemical concept into a feasible experimental plan, providing solid human resources support for clients' projects.

Advanced Facilities, Forging Quality

To meet the needs of high - end chemical synthesis, CD Hitech has invested heavily in the construction of laboratory hardware, creating a modern experimental space of over 5,000 square meters. It is equipped with a series of top - notch instruments and equipment. Mass spectrometry (MS) and nuclear magnetic resonance (NMR) can accurately analyze molecular structures. Ultra - high - performance liquid chromatography (UPLC), preparative high - performance liquid chromatography (prep - HPLC), and medium - pressure preparative chromatography (MPLC) can achieve the rapid separation and preparation of high - purity compounds. Microwave reactors accelerate chemical reactions and improve synthesis efficiency. The coordinated operation of these advanced devices ensures the accuracy of experimental data and the high quality of experimental results.

Data Security, Convenient Sharing

The company adopts the standardized Scilligence ELN experimental record system and RegMol compound registration system, constructing a tight data security protection network. From the real - time entry of experimental records to the accurate registration of compound information, every link is carefully designed. It not only ensures the security and integrity of data but also supports clients to remotely access and obtain experimental progress at any time, enabling efficient communication and collaboration.

Diverse Services, Customized Solutions

Conventional Chemical Synthesis Services

1.  Off - DNA DEL Molecule Synthesis: We use advanced technical means to accurately construct Off - DNA DEL molecule libraries, providing a rich variety of molecular entities for drug target screening and helping clients accelerate the drug discovery process.

2. Macrocycle Molecule Synthesis: With a deep understanding of macrocycle chemistry, we synthesize Macrocycle molecules with unique structures and biological activities to meet the special needs of clients in complex drug R&D.

3. PROTAC Molecule Synthesis: We are proficient in PROTAC technology and synthesize targeted protein degradation chimeric molecules, opening up a new path for innovative drug R&D.

4. Heterocycle Molecule Synthesis: Focusing on the synthesis of heterocyclic compounds, we introduce novel chemical skeletons for drug molecule design by taking advantage of the diversity of heterocyclic structures.

5. Conjugate Molecule Synthesis: Through precise linking chemistry, we achieve the efficient coupling of different molecular fragments to synthesize Conjugate molecules with specific functions.

6. Probe Molecule Synthesis: We design and synthesize various probe molecules for biological activity research and target validation, providing key tools for drug R&D.

Chemical Synthesis Services on Special Technology Platforms

1.  Automated Synthesis: We introduce advanced automated synthesis equipment to achieve high - throughput and standardized chemical reactions. While improving synthesis efficiency, we ensure the consistency and repeatability of experimental results.

2. Solid - Phase Synthesis: Taking advantage of the solid - phase synthesis technology, we simplify the synthesis steps and shorten the reaction cycle, which is especially suitable for the construction of large - scale compound libraries and the synthesis of complex molecules.
   

HitGen provides one - stop chemical synthesis solutions for global clients with its professional team, advanced facilities, complete data management system, and diverse services. We look forward to working with you to jointly explore and create more possibilities on the path of drug R&D.