HitGen offers comprehensive solutions for the development of oligonucleotide therapeutics, covering the entire process from research and development to production.
By integrating phosphorothioate backbone, 2’-OMe/F modifications on ribose, and a comprehensive chemical modification system, we construct differentiated pattern designs and implement unique conformational constraint strategies to overcome critical bottlenecks (stability, immunogenicity, off-target side effects) in nucleic acid drug development. This platform provide low intellectual property (IP) risk solutions via patent-definable chemical modification strategy.
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