Welcome to HitGen

成都先导

做最具创新力的生物医药企业     用最先进的科学技术赋能创新药研发

  1. 关于我们
  2. 发表文章

Synthesis of Multifunctional 2-Aminobenzimidazoles on DNA via Iodine-Promoted Cyclization 发布时间:2020-01-30

摘要:


2-Aminobenzimidazole cores are among the most common structural components in medicinal chemistry and can be found in many biologically active molecules. Herein, we report a mild protocol for the synthesis of multifunctional 2-aminobenzimidazoles on-DNA with broad substrate scopes. The reaction conditions expand our ability to design and synthesize 2-aminobenzimidazole core-focused DNA-encoded libraries.



Org. Lett. 2020, 22, 4, 1290–1294

https://doi.org/10.1021/acs.orglett.9b04578

Link:https://pubs.acs.org/doi/10.1021/acs.orglett.9b04578


联系我们

业务咨询与服务
提交此表格即表示我同意成都先导可以按照隐私政策说明中所述的方式收集、处理我的数据。

为了使您在浏览本网站时获得最佳的体验,您需同意我们对Cookies的使用。想要了解更多有关于Cookies的信息,请阅读我们的 隐私政策。