Welcome to HitGen

About

Enable Innovative Drug Discover with DEL, FBDD and SBDD

  1. About
  2. Publications

Publications

  • 01 August 2020
    A B2(OH)4-Mediated Synthesis of 2-Substituted Indazolone and Its Application in a DNA-Encoded Library
    Org. Lett. 2020, 22, 16, 6277–6282 https://doi.org/10.1021/acs.orglett.0c02032
  • 18 June 2020
    A Simple Method for Determining Compound Affinity and Chemical Yield From DNA-encoded Library Selections
    Biochemical and Biophysical Research Communications Volume 527, Issue 1, 18 June 2020, Pages 250-256
  • 27 April 2020
    Optimized Methods for IL-17A Refolding and anti-IL17A Fab Production for Co-Crystallization With Small Molecules
    BIOTECHNIQUESVOL. 69, NO. 1 https://doi.org/10.2144/btn-2019-0170
  • 10 April 2020
    Characterization of Specific N-α-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library
    ACS Med. Chem. Lett. 2020, 11, 6, 1175–1184 https://doi.org/10.1021/acsmedchemlett.0c00029
  • 02 April 2020
    Photocatalytic [2 + 2] Cycloaddition in DNA-Encoded Chemistry
    Org. Lett. 2020, 22, 8, 2908–2913 https://doi.org/10.1021/acs.orglett.0c00574
  • 12 February 2020
    RASS‐Enabled S/P−C and S−N Bond Formation for DEL Synthesis
    Angew. Chem. Int. Ed. 2020, 59, 7377 https://doi.org/10.1002/anie.201915493
  • 30 January 2020
    Synthesis of Multifunctional 2-Aminobenzimidazoles on DNA via Iodine-Promoted Cyclization
    Org. Lett. 2020, 22, 4, 1290–1294 https://doi.org/10.1021/acs.orglett.9b04578
  • 20 December 2019
    Exploring the Lower Limit of Individual DNA-Encoded Library Molecules in Selection
    SLAS Discov., 2019, 25, 5, 523-529 DOI: 10.1177/2472555219893949
  • 14 August 2019
    Synthesis of C3-Alkylated Indoles on DNA via Indolyl Alcohol Formation Followed by Metal-Free Transfer Hydrogenation
    Org. Lett. 2019, 21, 17, 6633–6637 https://doi.org/10.1021/acs.orglett.9b02132
  • 21 June 2019
    On-DNA Decarboxylative Arylation: Merging Photoredox with Nickel Catalysis in Water
    ACS Comb. Sci. 2019, 21, 8, 588–597 https://doi.org/10.1021/acscombsci.9b00076

Thanks for reading!

For more details on how we can advance your innovative drug discovery projects
验证码
By submitting your information, you acknowledge having received, read and understood our Privacy Notice as made available above.

We use cookies to provide a better web experience.
By using our site, you acknowledge our use of cookies and please read our Cookie Notice for More information