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Abstract：
2-Aminobenzimidazole cores are among the most common structural components in medicinal chemistry and can be found in many biologically active molecules. Herein, we report a mild protocol for the synthesis of multifunctional 2-aminobenzimidazoles on-DNA with broad substrate scopes. The reaction conditions expand our ability to design and synthesize 2-aminobenzimidazole core-focused DNA-encoded libraries.
Org. Lett. 2020, 22, 4, 1290–1294
https://doi.org/10.1021/acs.orglett.9b04578
Link：https://pubs.acs.org/doi/10.1021/acs.orglett.9b04578
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