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  • 04 December 2021
    Richard Lerner Remembrance
    It is with great sadness that we hear of the passing of Professor Richard A Lerner. Richard served as the director of the Scripps Research Institute from 1991 until 2012, and in 1992 published the seminal paper in PNAS describing the concept of recording a series of chemical transformations by a DNA “code” with his Scripps colleague and Nobel laureate Dr. Sidney Brenner (1927-2019).
  • 29 December 2020
    Exploring Aldol Reactions on DNA and Applications to Produce Diverse Structures: An Example of Expanding Chemical Space of DNA-Encoded Compounds by Diversity-Oriented Synthesis.
    Chem. Asian J. 2020, 15, 4033 https://doi.org/10.1002/asia.202001105
  • 03 December 2020
    A Method for Estimating Binding Affinity From Primary DEL Selection Data
    Biochemical and Biophysical Research Communications Volume 533, Issue 2 DOI: 10.1101/2020.05.04.077842
  • 01 August 2020
    A B2(OH)4-Mediated Synthesis of 2-Substituted Indazolone and Its Application in a DNA-Encoded Library
    Org. Lett. 2020, 22, 16, 6277–6282 https://doi.org/10.1021/acs.orglett.0c02032
  • 18 June 2020
    A Simple Method for Determining Compound Affinity and Chemical Yield From DNA-encoded Library Selections
    Biochemical and Biophysical Research Communications Volume 527, Issue 1, 18 June 2020, Pages 250-256 https://doi.org/10.1016/j.bbrc.2020.04.024
  • 27 April 2020
    Optimized Methods for IL-17A Refolding and anti-IL17A Fab Production for Co-Crystallization With Small Molecules
    BIOTECHNIQUESVOL. 69, NO. 1 https://doi.org/10.2144/btn-2019-0170
  • 10 April 2020
    Characterization of Specific N-α-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library
    ACS Med. Chem. Lett. 2020, 11, 6, 1175–1184 https://doi.org/10.1021/acsmedchemlett.0c00029
  • 02 April 2020
    Photocatalytic [2 + 2] Cycloaddition in DNA-Encoded Chemistry
    Org. Lett. 2020, 22, 8, 2908–2913 https://doi.org/10.1021/acs.orglett.0c00574
  • 30 January 2020
    Synthesis of Multifunctional 2-Aminobenzimidazoles on DNA via Iodine-Promoted Cyclization
    Org. Lett. 2020, 22, 4, 1290–1294 https://doi.org/10.1021/acs.orglett.9b04578
  • 20 December 2019
    Exploring the Lower Limit of Individual DNA-Encoded Library Molecules in Selection
    SLAS DISCOVERY: Advancing the Science of Drug Discovery. 2020;25(5):523-529. DOI:10.1177/2472555219893949


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