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Enable Innovative Drug Discover with DEL, FBDD and SBDD

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  2. Publications


  • 10 May 2021
    Functionalization of DNA-Tagged Alkenes Enabled by Visible-Light- Induced C−H Activation of N‑Aryl Tertiary Amines
    Org. Lett., 2021, 23(9), 3486-3490 https://doi.org/10.1021/acs.orglett.1c00924
  • 30 March 2021
    Development and Validation of High-Content Analysis for Screening HDAC6-Selective Inhibitors
    SLAS Discov:Development and Validation of High-Content Analysis for Screening HDAC6-Selective Inhibi https://10.1177/24725552211002463
  • 15 March 2021
    C–S Coupling of DNA-Conjugated Aryl Iodides for DNA-Encoded Chemical Library Synthesis
    Bioconjugate Chem. 2021 https://doi.org/10.1021/acs.bioconjchem.1c00076
  • 09 March 2021
    Cholesterol-Modified Oligonucleotides as Internal Reaction Controls during DNA-Encoded Chemical Library Synthesis
    Bioconjugate Chem. 2021 https://doi.org/10.1021/acs.bioconjchem.1c00045
  • 11 February 2021
    Employing Photocatalysis for the Design and Preparation of DNA‐Encoded Libraries: A Case Study
    Chem. Rec. 2021, 21, 616 https://doi.org/10.1002/tcr.202000148
  • 28 January 2021
    Application of imiquimod-induced murine psoriasis model in evaluating interleukin-17A antagonist
    BMC Immunol . 2021 Jan 28;22(1):11 10.1186/s12865-021-00401-3
  • 08 January 2021
    Selecting Approaches for Hit Identification and Increasing Options by Building the Efficient Discovery of Actionable Chemical Matter from DNA-Encoded Libraries
    DISCOVERY: Advancing the Science of Drug Discovery, vol. 26, no. 2, Feb. 2021, pp. 263–280 https://doi.org/10.1177/2472555220979589
  • 03 December 2020
    A Method for Estimating Binding Affinity From Primary DEL Selection Data
    Biochemical and Biophysical Research Communications Volume 533, Issue 2 DOI: 10.1101/2020.05.04.077842
  • 03 December 2020
    A method for estimating binding affinity from primary DEL selection data
    Res Commun. 2020 Dec 3;533(2):249-255 10.1016/j.bbrc.2020.04.029
  • 01 December 2020
    Exploring Aldol Reactions on DNA and Applications to Produce Diverse Structures: An Example of Expanding Chemical Space of DNA-Encoded Compounds by Diversity-Oriented Synthesis.
    Chem. Asian J. 2020, 15, 4033. https://doi.org/10.1002/asia.202001105

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