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Enabling Innovative Drug Discovery with Advanced Technologies

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  2. CRISPR

CRISPR

With its simplicity, versatility and almost unlimited gene editing opportunities, CRISPR/Cas9 technologies have transformed drug discovery and development. Throughout the early drug discovery stage, CRISPR/Cas9 has been proven to create more predictive cell-based models and revealed new drug targets. Several targets were validated using CRISPR/Cas9 at HitGen.


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Gene KO effect evaluation by proliferation assay


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Gene overexpression by Lentivirus

Gene overexpression stable cell lines are one of the widely used tools in target validation. Lentivirus vectors are the method of choice whenever a fast, efficient and cost-effective generation of stable cell models is required. Hitgen provides stable expression of a gene of interest (GOI) by lentivirus transduction.


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