Detailed pharmacokinetics information is required during the optimization stage, especially for compounds at the later stages of optimization. HitGen provides professional pharmacokinetic study services for lead compounds including animal experiments, bioanalysis, PK parameter estimation and data interpretation.
Full PK screening:
Multiple species: Mouse, Rat, Dog
Different dosing route: IV, IG, IP, SC, etc.
All PK parameter: Half-life, AUClast, AUCPred, Cmax, Tmax, MRT, Vz, Cl, etc.