Welcome to HitGen


One-stop Technology Platform to Accelerate Drug Discovery and Development

  1. Capabilities
  2. DEL Oligo Design and Synthesis

DEL Oligo Design and Synthesis

The key point of construction in DNA-Encoded Library technology is the encoded DNA sequences (termed ‘codon’ sequence). The codon sequence records the corresponding building block's information, and with the addition of a primer can do PCR amplification. The DNA coding sequence information can then be ‘read’ by a high-throughput sequencer. Finally, the enrichment hit can be identified after the screening. HitGen can provide codon sequence design and synthesis as a one-stop service. The codon sequence is designed according to the connection mode and the dimensions of the DNA-encoded library. The principle of codon design includes considering GC content, the balance of ATCG bases, palindrome, hairpins, the number of identical consecutive bases and repeat base pairs, enough pairwise distance to distinguish different codon, etc. HitGen can currently provide >50,000 qualified codon sequences.

资源 6.jpg

Thanks for reading!

For more details on how we can advance your innovative drug discovery projects
By submitting your information, you acknowledge having received, read and understood our Privacy Notice as made available above.

We use cookies to provide a better web experience.
By using our site, you acknowledge our use of cookies and please read our Cookie Notice for More information