Target feasibility analysis are applied throughout the target nomination and hit identification step. A feasible therapeutic target is evaluated in multiple aspects as listed below.
Literature review of the target to gain enough understanding of the target. The biological evidence as a therapeutic target, the mechanism of action, and the biological assays are all assessed in this stage.
A comprehensive review of the market and the competitive products. Differentiation is emphasized when determine the target product profile.
HitGen is equipped with multiple drug discovery platforms including but not limited to DEL, FBDD/SBDD, CADD, and siRNA platform. Our analysts will determine the most optimal method (or methods) to use based on the characteristics of the target.