Bioinformatics

HitGen Sequencing and bioinformatics core facility is equipped with the NovaSeq 6000 and HiSeq 2500, and several dedicate servers deployed with the state-of-the-art pipelines that are capable of analyzing huge volume of NGS-based sequencing data. The list of the platforms and the level of the analysis are described as followed.

1. You Li, Ye Wang, et al. SARS-CoV-2 Spike Glycoprotein Receptor Binding Domain is Subject to Negative Selection with Predicted Positive Selection Mutations. BioRxiv 2020.05.04.077842; doi: https://doi.org/10.1101/2020.05.04.077842

2. Jianan Xu, Ye Wang, You Li, Huiping Yang, Ming Pan, Jian Liu, Lina Shi, Yuliang Feng, Li Liu, Jin Li, Li Zhang, Shusen He. A Case Study of Applying Metagenomic Sequencing in Precise Epidemiology for the COVID-19 Pandemic — Sichuan Province, China, 2020[J]. China CDC Weekly, 2020, 2(47): 897-901. doi: 10.46234/ccdcw2020.244